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Each reglan 10 mg tablet contains 10 mg metoclopramide equivalent to 11.

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Treatment with metoclopramide can cause tardive dyskinesiaa serious movement disorder that is often irreversibleThe risk of developing tardive dyskinesia increases with duration of treatment and total cumulative dose.

There are insufficient reliable data to conclude whether the pharmacokinetics of metoclopramide in adults and the pediatric population are similarAlthough there are insufficient data to support the efficacy of metoclopramide in pediatric patients with symptomatic gastroesophageal refluxGERor cancer chemotherapy-related nausea and vomitingits pharmacokinetics have been studied in these patient populations.

The safety profile of metoclopramide in adults cannot be extrapolated to pediatric patientsDystonias and other extrapyramidal reactions associated with metoclopramide are more common in the pediatric population than in adultsSee WARNINGS and ADVERSE REACTIONSExtrapyramidal Reactions

Metoclopramide is also used in diabetic patients who have poor emptying of their stomachsgastroparesisTreating gastroparesis can decrease symptoms of nauseavomitingand stomach/abdominal fullnessMetoclopramide works by blocking a natural substancedopamineIt speeds up stomach emptying and movement of the upper intestines.

Reglan Injection is indicated for the prophylaxis of postoperative nausea and vomiting in those circumstances where nasogastric suction is undesirable.

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