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The results from an exploratory analysis indicated a worsening in keppra-treated patients on aggressive behavior one of eight behavior dimensions as measured in a standardized and systematic way using a validated instrument, the achenbach child behavior checklist cbcl 6-18 .

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No impact on fertility was detected in animal studiessee section 5.3No clinical data are availablepotential risk for human is unknown.

Serious dermatological reactionsincluding Stevens-Johnson syndromeSJSand toxic epidermal necrolysisTENhave been reported in both pediatric and adult patients treated with KEPPRAThe median time of onset is reported to be 14 to 17 daysbut cases have been reported at least four months after initiation of treatmentRecurrence of the serious skin reactions following rechallenge with KEPPRA has also been reportedKEPPRA should be discontinued at the first sign of a rashunless the rash is clearly not drug-relatedIf signs or symptoms suggest SJS/TENuse of this drug should not be resumed and alternative therapy should be considered.

Partial-onset seizures with or without generalisation in patients from one month of agemyoclonic seizuresshortshock-like jerks of a muscle or group of musclesin patients from 12 years of age with juvenile myoclonic epilepsyprimary generalised tonic-clonic seizuresmajor fitsincluding loss of consciousnessin patients from 12 years of age with idiopathic generalised epilepsythe type of epilepsy that is thought to have a genetic cause

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i began the keppra again just to guard against more seizures.