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Administer olanzapine and fluoxetine combination once daily in the evening, generally beginning with 2.

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Certain portions of the discussion below relating to objective or numeric safety parametersnamelydose-dependent adverse reactionsvital sign changesweight gainlaboratory changesand ECG changes are derived from studies in patients with schizophrenia and have not been duplicated for bipolar I disordermanic or mixed episodesor agitationHoweverthis information is also generally applicable to bipolar I disordermanic or mixed episodesand agitation.

Because clinical trials are conducted under widely varying conditionsadverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect or predict the rates observed in practice.

This document does not contain all possible interactionsThereforebefore using this producttell your doctor or pharmacist of all the products you useKeep a list of all your medications with youand share the list with your doctor and pharmacistCheck with your physician if you have health questions or concerns.

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seizures have also been reported with both olanzapine and fluoxetine monotherapy.