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ZETIA reduces total-CLDL-CApo Bnon-HDL-Cand TGand increases HDL-C in patients with hyperlipidemiaAdministration of ZETIA with a statin is effective in improving serum total-CLDL-CApo Bnon-HDL-CTGand HDL-C beyond either treatment aloneAdministration of ZETIA with fenofibrate is effective in improving serum total-CLDL-CApo Band non-HDL-C in patients with mixed hyperlipidemia as compared to either treatment aloneThe effects of ezetimibe given either alone or in addition to a statin or fenofibrate on cardiovascular morbidity and mortality have not been established.

Women of childbearing age should be advised to use an effective method of birth control to prevent pregnancy while using ZETIA added to statin therapyDiscuss future pregnancy plans with your patientsand discuss when to stop combination ZETIA and statin therapy if they are trying to conceivePatients should be advised that if they become pregnant they should stop taking combination ZETIA and statin therapy and call their healthcare professional.

EzetimibeZetiais a newly Food and Drug Administration(FDAapproved medication that selectively inhibits the intestinal absorption of cholesterol and related phytosterolsIt is approved for primary hypercholesterolemiaheterozygous familial and nonfamilial hypercholesterolemiaas monotherapy or in combination with 3-hydroxy-3-methylglutaryl coenzyme AHMG-CoAreductase inhibitorsstatinsIt is also indicated in combination with atorvastatin or simvastatin for homozygous familial hypercholesterolemia and as an adjunct to diet for homozygous sitosterolemia1

If you think there has been an overdosecall your poison control center or get medical care right awayBe ready to tell or show what was takenhow muchand when it happened.

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