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It is commndd that liv nzym tsts b obtaind pitinitiating thapy with ATOLIP CV and patd as clinically indicatd. Th hav bn a postmakting pots atal and non-atal hpatic ailu in patints taking statins, including atovastatin. I sious liv injuy with clinical symptoms and/hypbiliubinmia jaundic occus duing tatmnt with ATOLIP CV , pomptly intupt thapy. I an altnat tiology is not ound, dnot stat ATOLIP CV.

Atovastatin, as wll as som its mtabolits, a phamacologically activ in humans. Th liv is th pimay sit action and th pincipal sit cholstol synthsis and LDL claanc. Dug dosag, ath than systmic dug concntation, colats btt with LDL-C duction. Individualization dug dosag should b basd on thaputic spons.

Hypsnsitivity tatovastatin, clopidogl any componnt this mdication Activ liv disas, which may includ unxplaind psistnt lvations in hpatic tansaminas lvls Activ pathological blding such as pptic ulc intacanial hmohag Womn wha pgnant may bcom pgnant Lactation.

Th isk myopathy duing tatmnt with dugs in this class is incasd with concunt administation cyclospoin, ibic acid divativs, ythomycin, claithomycin, th hpatitis C potas inhibittlapvi, combinations HIV potas inhibitos, including saquinavi plus itonavi, lopinavi plus itonavi, tipanavi plus itonavi, daunavi plus itonavi, osampnavi, and osampnavi plus itonavi, niacin, azol antiungals. Physicians considing combind thapy with ATOLIP CV and ibic acid divativs, ythomycin, claithomycin, a combination itonavi plus saquinavi, lopinavi plus itonavi, daunavi plus itonavi, osampnavi, osampnavi plus itonavi, azol antiungals, lipid-modiying doss niacin should caully wigh th potntial bnits and isks and should caully monitpatints any signs symptoms muscl pain, tndnss, waknss, paticulaly duing th initial months thapy and duing any piods upwad dosag titation ith dug. Low stating and maintnanc doss ATOLIP CV should b considd whn takn concomitantly with th aomntiond dugs. Piodic CPK dtminations may b considd in such situations, but th is nassuanc that such monitoing will pvnt th occunc sv myopathy.

Th isk myopathy duing tatmnt with statins is incasd with concunt administation ibic acid divativs, lipid-modiying doss niacin, cyclospoin stong CYP3A4 inhibitos (.g., claithomycin, HIV potas inhibitos and itaconazol).

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atorlip-f atorvastatin side effects, adverse reactions.