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The pump system should not be implanted until the patient’s response to bolus LIORESAL INTRATHECAL injection is adequately evaluatedEvaluationconsisting of a screening proceduresee Dosage and Administrationrequires that LIORESAL INTRATHECAL be administered into the intrathecal space via a catheter or lumbar punctureBecause of the risks associated with the screening procedure and the adjustment of dosage following pump implantationthese phases must be conducted in a medically supervised and adequately equipped environment following the instructions outlined in the Dosage and Administration section.

Except in overdose related emergenciesthe dose of LIORESAL INTRATHECAL should ordinarily be reduced slowly if the drug is discontinued for any reason.

Screening Patients should be infection-free prior to the screening trial with LIORESAL INTRATHECALbaclofen injectionbecause the presence of a systemic infection may interfere with an assessment of the patient’s response to bolus LIORESAL INTRATHECAL.

It is not known whether this drug is excreted in human milkAs a general rulenursing should not be undertaken while a patient is on a drug since many drugs are excreted in human milk.

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you should avoid driving automobiles and operating other hazardous equipment until you are certain that lioresal doesn t impair your alertness.