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The official prescribing information for plaquenil does state that the retinal changes may be irreversible and may include color vision changes, loss of visual acuity, and changes in visual fields.

Information about Plaquenil.
Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarialsIt is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritisIt helps to reduce painstiffnessand swelling in jointsIt may take several weeks before the beneficial effects of hydroxychloroquine for the treatment of rheumatoid arthritis are seen.
Do not dispose of medications in wastewatere.gdown the sink or in the toiletor in household garbageAsk your pharmacist how to dispose of medications that are no longer needed or have expired.
The most common visual symptoms attributed to the retinopathy arereading and seeing difficultieswordslettersor parts of objects missingphotophobiablurred distance visionmissing or blacked out areas in the central or peripheral visual fieldlight flashes and streaks.
The incidence of retinopathy has been reported to be higher when this maintenance dose is exceeded.
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